An important group of SANE nutraceuticals are lipotropics. They are a clinically proven way to help your body metabolize fat for fuel (aka burn fat). They have also been shown to help with PCOS and liver health. Here is a rundown of some of the most effective, safe, and clinically proven lipotropic nutrients to help relieve issues associated with PCOS, weight gain, and liver toxicity.
Inositol for Preventing Fatty Liver and PCOS
You may be familiar with common B vitamins such as vitamins B1 (thiamin), B2 (riboflavin) and B3 (niacin), but do you know what vitamin B8 — more known as inositol — can do for you?
Since the 1940’s this vitamin-like nutrient has been shown to assist in fat transportation and metabolism. This finding is significant, because without lipotropics like inositol, fats can get trapped in the liver. This can lead to severe problems such as cirrhosis and poor fat metabolism.
More recently, inositol has been shown to help normalize insulin levels and stabilize weight in women with “polycystic ovary syndrome” (PCOS). This is a condition defined by a cluster of symptoms in females, including obesity, insulin resistance, menstrual disorders, and the elevation of hormones such as testosterone.
Choline to Optimize Fat-Burning
An essential B vitamin, choline plays a role in the functioning of every cell in your body. Specifically, it is a special emulsifying nutrient that helps to break down cholesterol and prevents it from sticking to artery walls. It works in partnership with inositol to help the body utilize fats.
In a 2016 study of 3214 adults, researchers checked levels of dietary choline and betaine (see below) in obese, overweight, and normal-weight men and women. The obese participants had the lowest levels of choline and betaine in their bodies; the overweight group had moderately low levels; and the normal-weight group had normal levels of both nutrients. Also, the lower the levels of choline and betaine, the heavier the subjects were in weight and waist circumference. Putting these findings together, we’re left with the conclusion that sub-par levels of both lipotropics somehow interfere with fat-burning (especially around the belly) and the inability to maintain a lower setpoint and weight.
Methionine for Improved Cholesterol Control
This important amino acid speeds fat and cholesterol utilization and mobilizes fat from the liver to be released and used as energy. Methionine also helps the body synthesize carnitine (a fat burner) and is necessary for the synthesis of choline, making it indirectly involved in fat-burning.
In 2013, researchers at Louisiana State University Health Sciences Center published a review in Current Diabetes Reviews, noting that studies with methionine have been shown improve insulin sensitivity and prevent body weight gain.
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